Table 3.
Temporal trends in the prevalence of HCV-related outcomes among veterans with hepatitis C virus infection by gender
| Outcome | Men | Women | ||||
|---|---|---|---|---|---|---|
| APC (95% CI)+ | AAPC (95% CI)+ | Segment | APC (95% CI)+ | AAPC (95% CI)+ | P-value* | |
| Cirrhosis | ||||||
| 2000–2002 | 32.5 (28.1–37.1) | 12.5 (11.9–13.1) | 2000–2004 | 20.7 (16.0–25.6) | 11.6 (10.3–12.8) | 0.99 |
| 2002–2005 | 15.2 (13.1–17.4) | 2004–2013 | 7.7 (7.0–8.4) | |||
| 2005–2013 | 7.0 (6.8–7.2) | ---- | ---- | |||
| Decompensated cirrhosis | ||||||
| 2000–2002 | 26.3 (21.3–31.6) | 11.3 (10.5–12.1) | 2000–2003 | 22.5 (11.9–34.0) | 10.8 (8.8–12.9) | 0.99 |
| 2002–2005 | 11.8 (9.1–14.7) | 2003–2013 | 7.6 (6.7–8.4) | |||
| 2005–2013 | 7.6 (7.4–7.9) | |||||
| Hepatocellular cancer** | ||||||
| 2000–2010 | 23.0 (20.8–25.3) | 20.8 (19.2–22.4) | --- | --- | --- | --- |
| 2010–2013 | 13.7 (10.7–16.8) | --- | --- | --- | ||
APC – Annual percent change
AAPC – Average annual percent change
CI – confidence interval
+
All p-values are <0.01 indicating there is a significant change over time for each segment
*
P-value for test for parallelism comparing males vs. females
**
no values were reported for women due to no HCC diagnosed in 2000–2003