Table 1.
Baseline clinical and biochemical characteristics of patients with APAs and concurrent SCH
| Case n° | Age /sex | SBP/DBP (mmHg) |
No. of drugs before AVS |
Serum K mmol/L) |
Plasma aldosterone (pmol/L) |
PRA (ng/ ml per h) |
DRC (mU/L) |
ARR | ACTH (pmol/L) |
Urinary Cortisol (nmol/24 h) |
Serum cortisol (nmol/L) |
Serum cortisol by 1 mg DST (nmol/L) |
CT scan | Laterality at AVS |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 51/F | 149/90 | 2 | 2.5 | 1387.2 | 9.4 | 147.5 | 1.32 | 456 | 278.3 | 187.6 | Right nodule | Right APA Right SCH | |
| 2 | 63/F | 144/98 | 2 | 2.8 | 1409.1 | 7.9 | 178.3 | 0.44 | 339 | 303.1 | 190.1 | Right nodule | Right APA Right SCH | |
| 3 | 64/M | 187/106 | 4 | 2.8 | 1687.9 | 10.9 | 154.8 | 0.88 | 554 | 942.5 | 96.4 | Left nodule | Left APA Left SCH | |
| 4 | 43/F | 170/102 | 3 | 1.9 | 1054.2 | 0.2 | 5271 | 2.86 | 937 | 355.5 | 104.7 | Left nodule | NA | |
| 5 | 72/M | 180/100 | 3 | 2.9 | 1095.7 | 0.1 | 10957 | 1.54 | 885 | 509.8 | 77.1 | Right nodule | NA |
Serum K refers to the lowest measured concentration
SBP systolic blood pressure, DBP diastolic blood pressure, PRA plasma renin activity, DRC direct renin concentration, ARR aldosterone-to-renin ratio, DST dexamethasone suppression test, CT computed tomography, AVS adrenal venous sampling, SCH subclinical cortisol hypersecretion, NA not available