Table 3.
Histopathological and genetic findings of APAs with concurrent SCH
| Case n° | Tumor size (mm) | Microscopic evaluation | Predominant cell pattern | CYP11B1H-score | CYP11B2H-score | Mutational status |
|---|---|---|---|---|---|---|
| 1 | 12 | Single nodule | ZF-like cells | 150 | 0 | PRKACA pLeu206Arg |
| 2 | 32 | Single nodule | ZF-like cells | 0 | 40 | WT |
| 3 | 11 | Single nodule | ZG-like cells | 15 | 180 | WT |
| 4 | 50 | Single nodule | ZF-like cells | 160 | 30 | WT |
| 5 | 40 | Single nodule with adjacent tissue containing multiple micronodules | ZF-like cells | 240 | 15 | CTNNB1 pSer45Phe |
ZF zona fasciculata, ZG zona glomerulosa, WT wild type