Figure 6.

Infection classification scheme for secondary children in the study. Primary infection among secondary children was defined as those without viral DNA detected at the beginning of the study who either showed seroconversion or were seronegative and met the PCR-based definition of primary infection³¹. Children with minimal evidence of virus by PCR (<2 positive oral swabs, 0 positive plasma samples) and no positive serology were considered uninfected and excluded from shedding analysis for that virus. All remaining children were considered chronically infected.