Table 4. Cut-off 4-hour post-ERCP lipase levels for predicting PEP.
| Cut-off value | Sensitivity | Specificity | PPV | NPV |
|---|---|---|---|---|
| Lipase level > 8 × ULR | 12/16 (75.0) | 457/500 (91.4) | 12/55 (21.8) | 457/461 (99.1) |
| Lipase level > 5 × ULR | 13/16 (81.3) | 443/500 (88.6) | 13/70 (18.6) | 443/446 (99.3) |
| Lipase level > 4 × ULR | 13/16 (81.3) | 430/500 (86.0) | 13/83 (15.7) | 430/433 (99.3) |
| Lipase level > 3 × ULR | 14/16 (87.5) | 411/500 (82.2) | 14/103 (13.6) | 411/413 (99.5) |
| Lipase level > 2 × ULR | 15/16 (93.8) | 373/500 (74.6) | 15/142 (10.6) | 373/374 (99.7) |
Values are presented as number (%).
ERCP = endoscopic retrograde cholangiopancreatography, PEP = post-ERCP pancreatitis, PPV = positive predictive value, NPV = negative predictive value, ULR = upper limit of reference.