Fig. 4. Histopathological analysis with H&E staining. Histological analysis of spinal cord lesions stained with H&E. (A) MSC-GFP group; upon magnification of the injury epicenter, fibroblast-like cell proliferation was detected. (B) MSC-HO-1 group; spinal cord lesion was limited to the compression region and a greater reduction in fibrotic changes was observed compared with those in the MSC-GFP group. Also, upon magnification, a reduction in fibroblast-like cell proliferation was observed. (C) Quantification of fibrotic tissue was showed significant difference between groups (*p < 0.05). 40× (top panels of A and B), 200× (bottom panels of A and B; enlargements of squares of the middle panels).
