Table 2. Characteristics of Different Patient Groups According to CDAI in CTE Surveillance Cohort.
Parameters | CDAI < 150 (n = 51) | CDAI ≥ 150 (n = 37) | P |
---|---|---|---|
Demographics and clinical features | |||
Age at diagnosis of CD, year (mean ± SD) | 25.8 ± 8.0 | 28.0 ± 10.4 | 0.254 |
Age at surgery, year (mean ± SD) | 30.0 ± 8.3 | 33.8 ± 10.9 | 0.040 |
Sex | 0.646 | ||
Male | 36 | 24 | |
Female | 15 | 13 | |
CDAI at CTE (mean ± SD) | 86.1 ± 40.9 | 226.4 ± 62.9 | < 0.001 |
Major risk factors for postsurgical disease recurrence/aggravation | |||
Smoking | 0.065 | ||
Never or ex-smoker | 40 | 35 | |
Active smoker | 11 | 2 | |
Previous CD-related bowel resection | 1.000 | ||
Yes | 13 | 9 | |
No | 38 | 28 | |
Indication for surgery | 1.000 | ||
Bowel penetration/perforation | 39 | 28 | |
Others* | 12 | 9 |
Data are from time of bowel resection surgery and number of patients unless specified otherwise. *Include obstruction/stricture and failure of medical therapy. CDAI = Crohn's disease activity index