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. 2017 Oct 6;31(10):1399–1408. doi: 10.1038/eye.2017.180

Figure 4.

Figure 4

Choriocapillaris involvement exceeds detectable retinal structural changes (right eye of Patient 5). OCT-A image (a) at the level of the choriocapillaris (parallel horizontal red lines in b) revealed focal areas of hypoperfusion in the right eye of Patient 5. Corresponding SD-OCT scan (b) at the level of the green line on the OCT-A image (a1) revealed associated abnormalities in the outer retinal layers and RPE. The outer border of the area of hypoperfusion on OCT-A was seen to extend to a greater extent than the OCT B-scan abnormalities (corresponding locations in a and b images are identified by vertical red lines). In the early evolution of the lesions the area of hypoperfusion in the OCT-A increased in size (a2), whereas the SD-OCT findings reveal qualitative outer retinal thinning (b2). With time the area of hypoperfusion at the level of the choriocapillaris improves (a3, 4) and the thinning of the outer retina in SD-OCT persists (b3, 4). Corresponding en face-OCT at the level of the choriocapillaris at each time point is presented in the bottom row (c1–4). A full color version of this figure is available at the Eye journal online.