Table 4. Summary of multivariate logistic regression models examining AFE to football and clinically meaningful scores on measures of behavior, mood and cognitive function.

214 Former American football players
	AFE dichotomized (1, <12; 0, ⩾12)				Continuous AFE
Clinical tests	OR	95% CI	P	Adj. Pa	OR	95% CI	P	Adj. Pa
BRIEF-A BRI	2.16	1.19, 3.91	0.011	0.016	0.89	0.79, 1.01	0.08	0.10
BRIEF-A MI	2.10	1.17, 3.76	0.013	0.016	0.89	0.78, 1.00	0.05	0.09
BTACT	1.43	0.46, 4.41	0.54	0.54	0.94	0.75, 1.18	0.62	0.62
AES	2.39	1.32, 4.32	0.004	0.010	0.86	0.76, 0.97	0.014	0.046
CES-D	3.08	1.65, 5.76	<0.001	0.002	0.85	0.74, 0.97	0.018	0.046

Abbreviations: Adj, adjusted; AES, Apathy Evaluation Scale; AFE, age of first exposure; BRI, Behavioral Regulation Index; BRIEF-A, Behavior Rating Inventory of Executive Function-Adult Version; BTACT, Brief Test of Adult Cognition by Telephone; CES-D, Center for Epidemiologic Studies Depression Scale; CI, confidence interval; MI, Metacognition Index; OR, odds ratio.

Clinical tests were dichotomized into impaired or not impaired using established cutoffs; higher scores reflect clinical impairment. Analyses adjusted for age, years of education and seasons of football play. A factor of 100 was applied to the BTACT to facilitate model fit.

^aP-values are adjusted for multiple comparisons via the false discovery rate method. The bold is used for those P values that are significant.