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. 2017 Sep 19;7(9):e1233. doi: 10.1038/tp.2017.205

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Copyright © 2017 The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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hBDNF^Val66Met genotype and chronic CORT exposure interact to selectively reduce the expression of Tyrosine Hydroxylase (TH) and calretinin in the mPFC but not hippocampus. While there was no effect of genotype or chronic CORT treatment on TH (a, b) or calretinin (d, e) expression in the DHP or VHP, the expression of both TH (c) and calretinin (f) was found to be reduced in hBDNF^Val/Val mice following CORT in the mPFC. All data are presented as mean±s.e.m.; *P<0.05, **P<0.01, ***P<0.001 and ****P<0.0001. Per group, n=13–14.