Table 6. Differential plasma metabolites between control and PD groups at age 18.
| Metabolite name | Control (n=117) | Cases (n=36) | P-value | FDR-adjusted |
|---|---|---|---|---|
| 1-Monopalmitin | 312.8±129.67 | 254.3±112.61 | 0.012 | 0.323 |
| 2-Hydroxybutyric acid | 577.68±232.1 | 489.04±213.93 | 0.0161 | 0.323 |
| 3-Hydroxybutyric acid | 36.64±37.35 | 25.76±23.78 | 0.0464 | 0.369 |
| Cholesterol | 359.7±82.18 | 335.36±75.08 | 0.0165 | 0.323 |
| Citric acid | 7.22±2.98 | 5.85±2.36 | 0.0329 | 0.346 |
| Glycine | 11.52±3.19 | 12.07±3.79 | 0.0374 | 0.346 |
| Leucine | 13.13±3.34 | 11.23±2.72 | 0.412 | 0.346 |
| l-tryptophan | 14.95±7.76 | 12.12±8.77 | 0.0411 | 0.346 |
| Oleic acid | 88.13±30.34 | 79.9±25.78 | 0.0344 | 0.346 |
| Palmitic acid | 105.31±23.19 | 97.2±16.08 | 0.0171 | 0.323 |
| Scyllo-inositol | 79.11±102.3 | 51.76±40.75 | 0.0215 | 0.325 |
| Stearic acid | 35.94±8.4 | 32.93±6.74 | 0.0275 | 0.346 |
| Sugar derivative | 1666.31±517.3 | 1474.28±530.76 | 0.0288 | 0.346 |
| A144004 | 416±242.81 | 314.94±301.41 | 0.0125 | 0.323 |
| Sugar derivative | 1253.88±362.07 | 1076.74±395.7 | 0.0137 | 0.323 |
| Threonic acid | 1457.44±491.45 | 1294.07±599.63 | 0.02 | 0.325 |
| Sugar derivative | 916.23±283.49 | 840.44±324.57 | 0.0155 | 0.323 |
| Tocopherol, α | 453.34±307.71 | 353.09±133.91 | 0.0151 | 0.323 |
| Levoglucosan | 31.55±52.17 | 36.39±51.9 | 0.0356 | 0.346 |
Abbreviations: BMI, body mass index; FDR, false discovery rate; PD, psychotic disorder. Values are expressed as standard units±s.d. (standard deviation). P-values are adjusted for gender and BMI. FDR-adjusted P-values are adjusted for multiple comparisons using the Benjamini–Hochberg procedure.