Skip to main content
. Author manuscript; available in PMC: 2018 Sep 5.
Published in final edited form as: Biochemistry. 2017 Aug 24;56(35):4676–4688. doi: 10.1021/acs.biochem.7b00518

Table 1.

Analysis of Aggregation Based on the Integration of s* Distributionsa for C. elegans and D. Melanogaster HttQn Samples

sample % monomerb % aggregatesc
C. elegans HttQ28 30 70
C. elegans HttQ74   3 97
D. melanogaster HttQ25 34 66
D. melanogaster HttQ46 24 76
D. melanogaster HttQ72   7 93
D. melanogaster HttQ97 18 82
D. melanogaster HttQ25d 35.3 ± 0.8 64.7 ± 0.8
D. melanogaster HttQ46d 16.8 ± 4.8 83.2 ± 4.8
D. melanogaster HttQ72d   6.7 ± 1.7 93.3 ± 1.7
D. melanogaster HttQ97d 14.7 ± 1.9 85.6 ± 1.9
a

Expressed as a percentage of the complete integrated areas from 1 to 1000 S in Figure 3.

b

Based on integration of the 1–20 S area.

c

Based on integration of the 20–1000 S area.

d

Average monomer/aggregate percentages, combining all SV runs for each particular HttQn line, including different drivers and levels of Hsp70 expression (see Table 2) because these did not significantly change the distributions.