Table VIII.
MSCs | Pre-treatment | Scaffold | SCI Patients | Follow-up | Outcomes | (Refs.) |
---|---|---|---|---|---|---|
Autologous BMSCs | Resection surgery to eliminate the glial scar tissue | NeuroRegen™ | 5 chronic SCI with complete thoracic or cervical transection | One-year | ↑ Nerve regeneration; ↑ Autonomic nervous functions | (121) |
Allogenic UCMSCs | Resection surgery to eliminate the glial scar tissue | NeuroRegen™ | 8 chronic SCI with complete thoracic or cervical transection | One-year | Recovery of some autonomic neural function | (122) |
BMSCs, bone marrow-derived mesenchymal stem cells; UCMSCs, umbilical cord mesenchymal stem cells; SCI, spinal cord injury.