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. 2017 Aug 16;14(4):3355–3368. doi: 10.3892/etm.2017.4939

Table VIII.

Clinical studies with combined approach of scaffolds and MSCs in SCI regeneration.

MSCs Pre-treatment Scaffold SCI Patients Follow-up Outcomes (Refs.)
Autologous BMSCs Resection surgery to eliminate the glial scar tissue NeuroRegen™ 5 chronic SCI with complete thoracic or cervical transection One-year ↑ Nerve regeneration; ↑ Autonomic nervous functions (121)
Allogenic UCMSCs Resection surgery to eliminate the glial scar tissue NeuroRegen™ 8 chronic SCI with complete thoracic or cervical transection One-year Recovery of some autonomic neural function (122)

BMSCs, bone marrow-derived mesenchymal stem cells; UCMSCs, umbilical cord mesenchymal stem cells; SCI, spinal cord injury.