Table 1.
Characteristics of IV tPA-treated Acute Ischemic Stroke Cases with Door-to-Needle time ≤60 minutes and Door-to-needle >60 minutes in the FL-PR Stroke Registry, 2010–2015
| DTNT ≤ 60 min (N=2605, 42%) | DTNT > 60 min (N=3576, 58%) | p | |
|---|---|---|---|
| Age (yrs), mean ± SD | 70.7 ± 8.2 | 70.7 ± 8.5 | |
| Women, n (%) | 1187 (46) | 1791 (50) | <.0001 |
| Race-ethnicity, n (%) | |||
| White | 1568 (60) | 2382 (67) | <.0001 |
| Black | 332 (13) | 530 (15) | |
| FL Hispanic | 499 (19) | 400 (11) | |
| PR Hispanic | 206 (8) | 264 (7) | |
| Region, n (%) | |||
| South FL | 1251 (48) | 1264 (35) | <.0001 |
| West Central FL | 334 (13) | 852 (24) | |
| East Central FL | 398 (15) | 588 (16) | |
| North & Panhandle | 416 (16) | 608 (17) | |
| Puerto Rico | 206 (8) | 264 (7) | |
| Vascular Risk Factor, n (%) | |||
| Hypertension | 1539 (59) | 2403 (67) | <.0001 |
| Diabetes mellitus | 538 (21) | 859 (24) | .002 |
| Medical History, n (%) | |||
| AF | 566 (22) | 795 (22) | 0.64 |
| CAD/prior MI | 496 (19) | 871 (24) | <.0001 |
| Previous stroke/TIA | 425 (16) | 806 (23) | <.0001 |
| NIHSS, n (%) | |||
| ≤5 | 512 (20) | 803 (22) | <.0001 |
| 6–15 | 1160 (45) | 1498 (42) | |
| ≥16 | 830 (32) | 1030 (29) | |
| Missing | 103 (4) | 245 (7) | |
| Arrival Mode, n (%) | |||
| EMS | 2144 (82) | 2736 (77) | <.0001 |
| Not by EMS | 222 (9) | 501 (14) | |
| Missing/Unknown | 239 (9) | 339 (9) | |
| Ambulation Status*, n (%) | |||
| Independent | 1410 (54) | 2280 (64) | <.0001 |
| With Assistance | 84 (3) | 163 (4) | |
| Missing/ND | 1111 (43) | 1133 (32) | |
| Hospital size, n (%) | |||
| Small (<250 beds) | 337 (13) | 560 (15) | .003 |
| Mid (≥250–450 beds) | 797 (31) | 992 (28) | |
| Large (>450 beds) | 1471 (56) | 2024 (57) | |
| Years in GWTG-S, mean±SD | 8.2 + 2.2 | 8.5 + 2.5 |
AF= Atrial fibrillation, CAD/MI=Coronary artery disease, MI=myocardial infarction, TIA=transient ischemic attack, NIHSS=National Institute of Health Stroke Scale, EMS=emergency medical services,
*
Ambulation prior to stroke