Table 1.
Immune profile of AML patients’ BM mononuclear cells
| % Relative to human CD45 | |||||
|---|---|---|---|---|---|
| Donor | No. of mononuclear cellsa injected per NSG pupb | CD45loCD34+ | CD45loCD34+CD33+CD117+ | CD45loCD34− | CD45loCD34−CD33+CD117+ |
| Leu 14 | 6.5 × 105 | 61.4 | 10.7 | 35.7 | 0.1 |
| Leu 29 | 2.9 × 105 | 3.1 | 0.0 | 8.6 | 0.0 |
| Leu 32 | 8.7 × 104 | 53.0 | 0.0 | 27.5 | 0.0 |
| Leu 33 | 2.6 × 105 | 1.1 | 0.0 | 15.5 | 0.0 |
| BMI 1690 | 5.0 × 105 | 56.1 | 1.2 | 32.7 | 5.5 |
| BMI 1786 | 7.9 × 105 | 72.0 | 1.0 | 19.3 | 0.0 |
| BMI 1808 | 6.7 × 105 | 34.7 | 3.6 | 50.3 | 14.1 |
aRefers to CD3-depleted mononuclear cells
bRefers to 1–3-day-old NSG newborn