Table 2.
Peds QoL Generic and Fatigue Scores: In relation to norms
| QoL Score, Mean | Children with CAH | Healthy Children | Mean difference (95% CI) | Parents, CAH Children | Parents, Healthy Children | Mean difference (95% CI) |
|---|---|---|---|---|---|---|
| Generic QoL Scores (Overall and subscales) | ||||||
| Overall | 82.71 (n = 32) | 83.00 (n = 401) | −0.29 (−.25, 5.67) | 83.90 (n = 43) | 87.61 (n = 717) | −3.71 (−7.37, −0.05)a |
| Physical | 90.53 (n = 32) | 84.41 (n = 400) | 6.12 (2.10, 10.14)a | 89.10 (n = 44) | 89.32 (n = 717) | −0.22 (−3.52, 3.08) |
| Emotional | 80.16 (n = 32) | 80.86 (n = 400) | −0.70 (−6.96, 5.55) | 75.90 (n = 44) | 82.64 (n = 717) | −6.74 (−12.36, −1.12)a |
| Social | 85.16 (n = 32) | 87.42 (n = 399) | −2.26 (−10.11, 5.58) | 90.60 (n = 43) | 91.56 (n = 716) | −0.96 (−4.57, 2.65) |
| School | 75.00 (n = 32) | 78.63 (n = 386) | −3.63 (−9.78, 2.52) | 78.99 (n = 40) | 85.47 (n = 611) | −6.48 (−12.75, −0.21)a |
| Fatigue Scores (Overall and subscales) | ||||||
| Overall | 79.08 (n = 32) | 80.49 (n = 52) | −1.41 (−7.85, 5.02) | 81.90 (n = 42) | 89.63 (n = 102) | −7.73 (−12.24, −3.22)a |
| General | 82.81 (n = 32) | 85.34 (n = 52) | −2.53 (−9.13, 4.07) | 82.40 (n = 42) | 89.30 (n = 102) | −6.90 (−12.34, −1.46)a |
| Sleep/Rest | 74.48 (n = 32) | 75.00 (n = 52) | −0.52 (−8.30, 7.25) | 81.60 (n = 42) | 88.86 (n = 102) | −7.26 (−12.14, −2.38)a |
| Cognitive | 79.97 (n = 31) | 81.14 (n = 52) | −1.17 (−10.71, 8.37) | 81.60 (n = 42) | 90.72 (n = 102) | −9.12 (−15.72, −2.52)a |
aIndicates a significant finding at the 0.05 significance level
CAH congenital adrenal hyperplasia, QoL quality of life