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. Author manuscript; available in PMC: 2017 Oct 13.
Published in final edited form as: Neurobiol Learn Mem. 2009 Nov 22;93(3):312–321. doi: 10.1016/j.nlm.2009.11.005

Figure 6.

Figure 6

Effect of post-training intra-BLA infusions of propranolol (0.5 μg/ 0.2 μL) on corticosterone-induced Arc expression in hippocampal synaptoneurosome fractions. A. Western blot densitometry values for Arc were normalized to actin, expressed as a ratio of the drug-infused hemisphere to the vehicle-infused hemisphere (or ratio of left-right hemisphere for bilateral, vehicle-infused rats), and are finally expressed as a percentage of the bilateral control group. For propranolol-treated rats (n=10), the percentage of Arc expression was significantly lower in hippocampal synaptoneurosome fractions than in synaptoneurosome fractions taken from bilateral vehicle-treated rats (n=7; *p<.05). B. In the top panel, immunohistochemistry illustrates a moderate reduction in Arc staining in the hippocampus ipsilateral to the intra-BLA propranolol infusion. Here, the reduction appears to be greater in the dentate gyrus and CA3 regions, however this pattern was not reliably observed. C. 20× magnification of the CA1 region of the dorsal hippocampus reveals a reduction in Arc staining in the dendritic regions of the hippocampus ipsilateral to the intra-BLA propranolol infusion. Data are presented as mean + SEM.