Fig. 5.

Distribution of histone marks across differentially expressed genes. a Profile of each indicated mark across the up-regulated genes (the dot and dash lines), divided into four sub-groups according to the FPKM value: less than 1, between 1 and 10, between 10 and 50, and greater than 50, and the corresponding untreated genes were used as controls (the solid lines); b Profile of each indicated mark across the down-regulated genes (the dot and dash lines), which were divided into three sub-groups according to the FPKM value: between 1 and 10, between 10 and 50, and greater than 50, and the corresponding untreated genes used as controls(the solid lines). The x-axis represents the position relative to TSS; the y-axis represents normalized reads counts from each mark indicated, indicating the enrichment of the corresponding mark