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. Author manuscript; available in PMC: 2018 Sep 1.
Published in final edited form as: Addict Biol. 2016 Apr 6;22(5):1169–1178. doi: 10.1111/adb.12399

Figure 2.

Figure 2

Time course of the discriminative stimulus effects of (±)-alpha-PVP (A; 0.01 – 0.32 mg/kg, IM), (±)-3,4-methylendioxypyrovalerone (MDPV) (B; 0.01 – 0.32 mg/kg, IM), and (±)-4-methylpyrrolidinovalerophenone (4MPVP) (C; 0.01 – 0.32 mg/kg, IM) in male rhesus monkeys (n=4). Abscissae: time in min after injection. Ordinates: percent cocaine-appropriate responding. Symbols above “S” and “C” represent the group averages for all saline- and cocaine-training sessions preceding test sessions, respectively. Filled symbols indicate statistical significance compared to saline at a given time point (p < 0.05). Number in parentheses indicate the number of subjects contributing to that data point if fewer than the total number (4) of subjects tested (i.e. indicative of a time point where one or more monkeys failed to complete at least one ratio requirement).