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. 2017 Oct 6;7(10):e014626. doi: 10.1136/bmjopen-2016-014626

Table 4.

Discounted results

Scenario Survival (LY) Total cost (K€) ICER (€/LY) versus current Frontier
IndScr only* 19.4 122.6 Reference Dominated
Pap/Pap-HPV +10.04 +22.3 22 234 Dominated
Pap/p16Ki67 +11.68 +25.5 21 918 Dominated
HPV/Pap-3y +15.93 +55.8 35 095 Dominated
HPV/Pap-5y +15.89 −13.3 Dominant Ext. Dominated
HPV/Pap-10y +10.51 −73.4 Dominant Reference
HPV/p16Ki67-5y +18.13 +3.79 2091 101 389
HPV/p16Ki67-10y +13.00 −64.6 Dominant 35 846
p16Ki67/p16Ki67 +18.37 +160.7 87 546 6 592 441

*Reference for other scenarios. Extra survival per 10 000 women eligible for OS on a lifetime horizon.

HPV, human papillomavirus; ICER, incremental cost-effectiveness ratio; IndScr, individual screening; LY, life years; OS, organised screening; Pap, Papanicolaou.