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. 2017 Oct 5;7(10):e016582. doi: 10.1136/bmjopen-2017-016582

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A linear relationship between the cumulative number of pack-years and NPC risk (p for linearity=0.83), with a 15% (95% CI 1.11 to 1.19, p<0.001) increasing risk of NPC for every additional 10 pack-years smoked in comparison with never smokers (the solid line depicts the pooled risk estimate of NPC associated with each 1 pack-year increment of cigarette smoking, the dashed line depicts the upper CI, the dot line depicts the lower CI). NPC, nasopharyngeal carcinoma.