Table 3.

Adverse event frequency measures and screening form performance

	Cross-sectional study			Retrospective study
	Positive screening review form	Positive predictive values	Prevalence of adverse events	Positive screening review form	Positive predictive values	Cumulative incidence of adverse events
Country 1	39.0% 926/2373 (95% CI 37.0% to 41.0%)	33.7% 312/926 (95% CI 30.6% to 36.8%)	13.1% 312/2373 (95% CI 11.8% to 14.5%)	61.7% 145/235 (95% CI 6.7% to 8.1%)	51.7% 75/145 (95% CI 43.2% to 60.2%)	31.9% 75/235 (95% CI 25.7% to 38.1%)
Country 2	30.6% 887/2897 (95% CI 28.9% to 32.3%)	25.3% 224/887 (95% CI 22.3% to 28.2%)	7.7% 224/2897 (95% CI 6.7% to 8.7%)	38.9% 112/288 (95% CI 33.1% to 44.7%)	32.1% 36/112 (95% CI 23.0% to 41.2%)	12.5% 36/288 (95% CI 8.5% to 16.5%)
Country 3	35.4% 578/1632 95% CI 33.1% to 37.8%)	34.3% 198/578 (95% CI 30.3% to 38.2%)	12.1% 198/1632 (95% CI 6.7% to 8.7%)	63.7% 107/168 (95% CI 56.1% to 71.3%)	57.0% 61/107 (95% CI 47.2% to 66.9%)	36.3% 61/168 (95% CI 28.7% to 43.9%)
Country 4	34.5% 692/2003 (95% CI 32.4% to 36.7%)	24.7% 171/692 (95% CI 21.4% to 27.9%)	8.5% 171/2003 (95% CI 7.3% to 9.8%)	46.9% 82/175 (95% CI 39.2% to 54.5%)	24.4% 20/82 (95% CI 14.5% to 34.3%)	11.4% 20/175 (95% CI 6.4% to 16.4%)
Country 5	31.1% 770/2474 (95% CI 29.3% to 32.9%)	37.1% 286/770 (95% CI 33.7% to 40.6%)	11.6% 286/2474 (95% CI 10.3% to 12.8%)	17.1% 38/222 (95% CI 11.9% to 22.3%)	60.5% 23/38 (95% CI 43.7% to 77.4%)	10.4% 23/222 (95% CI 6.1% to 14.6%)
Total	33.9% 3853/11379 (95% CI 32.9% to 34.7%)	30.9% 1191/3853 (95% CI 29.4% to 32.4%)	10.5% 1191/11379 (95% CI 9.9 to 11.0)	44.5% 484/1088 (95% CI 41.5% to 47.5%)	44.4% 215/484 (95% CI 39.3% to 48.3%)	19.8% 215/1088 (95% CI 17.3% to 22.2%)