Table 5.

Model 2: key drivers of direct costs in patients with tuberous sclerosis complex with epilepsy during the most recent 3-year period

Parameter*	p Value
Age (<18 and ≥18)	0.6089
Sex	0.2285
Manifestation categories (n)	<0.0001
1 manifestation* vs 2 manifestations†	0.3098
1 manifestation vs 3 manifestations‡	0.0495
1 manifestation vs ≥4 manifestations§	0.0059
2 manifestations vs 3 manifestations	0.0111
2 manifestations vs ≥4 manifestations	<0.0001
3 manifestations vs ≥4 manifestations	0.0101
1 manifestation* vs 2 manifestations†	0.3098

*n=34 for one manifestation.

†n=92 for two manifestations.

‡n=19 for three manifestations.

§n=5 for ≥4 manifestations.