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. 2017 Oct 6;7(10):e015112. doi: 10.1136/bmjopen-2016-015112

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Flow diagram of the study. In this study, the cases of 57 443 consecutive patients ≥18 years old who presented to Iizuka Hospital’s emergency department (ED) by an ambulance between 1 February 2006 and 30 September 2014 were evaluated. Excluded from the study were 391 patients who had repeated ED visits on 2 consecutive days, 2317 patients had a history of cardiopulmonary arrest and 298 were pregnant. Of the remaining 54 437 records, 12 830 patients were diagnosed with cardiovascular disease (CVD). Six hundred and nineteen (4.8%) patients whose high-sensitivity C reactive protein (hs-CRP) level or white cell count (WCC) at baseline was not obtained were excluded. A final total of 12 211 patients with CVD were included in this study. ICD 10, International Classification of Diseases, 10th Revision.