Table 6.

Cirrhosis-related clinical indicators’ effect on the outcomes of fracture admission in patients with liver cirrhosis

Characteristics of cirrhosis before fracture admission	30-day in-hospital adverse events*
	n	Events	Incidence, %	OR (95% CI)†
No LC	680 706	26 945	4.0	1.00 (reference)
Effects of liver admission
LC without liver admission	5068	401	7.9	1.65 (1.49 to 1.84)
LC with liver admission	2516	220	8.7	1.91 (1.65 to 2.20)
Effects of ADS
LC without ADS	6397	530	8.3	1.70 (1.55 to 1.86)
LC with ADS	1187	91	7.7	1.97 (1.58 to 2.45)
Effects of jaundice
LC without jaundice	7013	554	7.9	1.64 (1.50 to 1.80)
LC with jaundice	571	67	11.7	3.15 (2.42 to 4.10)
Effects of ascites
LC without ascites	6337	479	7.6	1.59 (1.45 to 1.75)
LC with ascites	1247	142	11.4	2.49 (2.08 to 2.98)
Effects of GI haemorrhage
LC without GI haemorrhage	5688	439	7.7	1.62 (1.46 to 1.79)
LC with GI haemorrhage	1896	182	9.6	2.09 (1.79 to 2.45)
Effects of hepatic coma
LC without hepatic coma	6587	503	7.6	1.59 (1.45 to 1.75)
LC with hepatic coma	997	118	11.8	2.77 (2.27 to 3.38)
Number of cirrhotic indicators‡
0	3772	254	6.7	1.36 (1.19 to 1.54)
1	2378	206	8.7	1.83 (1.58 to 2.12)
2	944	105	11.1	2.65 (2.15 to 3.27)
3	359	43	12.0	2.95 (2.12 to 4.09)
≥4	131	13	9.9	2.94 (1.64 to 5.29)

*Adverse events included 30-day in-hospital mortality, septicaemia, and acute renal failure.

†Controlled for all covariates listed in table 3.

‡Liver-related illnesses included alcohol dependence syndrome, ascites, jaundice, gastrointestinal haemorrhage, and hepatic coma.

ADS, alcohol dependence syndrome; CI, confidence interval; GI, gastrointestinal; LC, liver cirrhosis; OR, odds ratio.