Table 2.

Baseline characteristics and clinical data

Data	Description
Baseline characteristics	Sex and age Comorbidities Diabetes mellitus, cirrhosis of the liver, renal disease, heart disease, vascular disease, hepatitis, intravenous drug abuse, history of cancer, COPD, immunosuppression Body mass index Primary infection site Origin of infection Chronic wound, injection, boil/furuncle, animal bite, idiopathic, trauma, postoperative infection, perianal abscess, other Symptoms registered at the primary hospital Oedema, erythema, tachycardia, fever, bullae Responsible micro-organism Time between admission to primary hospital and first debridement Time between admission to primary hospital and admission to ICU Steroid treatment (injection/oral) prior to development of NSTI (Time frame: up to 7 days prior to surgical diagnosis at primary hospital) Other medication
Clinical data from the ICU	MAP (mm Hg) Heart rate (bpm) Arterial blood gas values: pO2, pCO2, HCO3−, base excess, pH K+, Na+, Ca2+, glucose, creatinine, haemoglobin, haematocrit Norepinephrine infusion Ventilator treatment Vasopressor treatment Renal replacement treatment LRINEC score

bpm, beats per minute; COPD, chronic obstructive pulmonary disease; ICU, intensive care unit; LRINEC, Laboratory Risk Indicator for Necrotising Fasciitis; MAP, mean arterial blood pressure; NSTI, necrotising soft tissue infection; pO₂, partial pressure of oxygen; pCO₂, partial pressure of carbon dioxide.