Table 2.

Eligibility criteria

Inclusion criteria

Exclusion criteria

Minimum age of 18 years Elective Endo-CABG procedure (group 1) Elective PCI procedure (group 2) Healthy volunteers (group 3)

Medical history of: Postoperative cognitive dysfunction, delirium or cerebrovascular accident Symptomatic carotid artery disease Dementia (score MMSE <20/30) Renal dysfunction: glomerular filtration rate <30 mL/min Hepatic dysfunction: serum glutamic oxaloacetic transaminase/aspartate aminotransferase or serum glutamic-pyruvic transaminase/alanine aminotransferase, more than three times higher than normal limits History of drug and/or alcohol abuse Language barrier or incapability to communicate Physical condition making participation impossible Participation in other clinical trials of a drug or medical instrument Surgical revision or intraoperative major cardiac event (Endo-CABG group) Conversion to cardiac surgery or major intraoperative adverse event (PCI group)

Endo-CABG, Endoscopic coronary artery bypass grafting; MMSE, Mini-Mental State Examination; PCI, percutaneous coronary intervention.