Table 4.

Multivariable logistic regression for evaluating variables associated with an optimal immunological outcome and conventional outcome

	Optimal immune outcome		Conventional outcome
	aOR	95% CI	aOR	95% CI
Male gender	2.23	1.4 to 3.53*	1.81	1.11 to 2.96*
Age at HAART initiation	0.98	0.97 to 0.9996*	0.96	0.94 to 0.97*
Pre-HAART CD4 (/μL)
≤100	Ref		Ref
101–200	2.91	1.83 to 4.62*	2.30	1.57 to 3.37*
201–300	4.61	2.53 to 8.39*	3.52	2.1 to 5.9*
>300	20.36	7.51 to 55.17*	12.84	3.6 to 45.75*
Months on treatment
49–72	Ref		Ref
73–96	1.58	0.93 to 2.67	1.67	1.08 to 2.57*
≥97	3.34	2.17 to 5.15*	2.78	1.89 to 4.09*
Pre-HAART CD8 ≤800/μL	0.998	0.998 to 0.999*
Constant	0.48		3.30

An optimal immunological outcome was defined as achieved CD4 count ≥500/μL and a CD4:CD8 ratio ≥0.8, and conventional outcome was defined as only achieved CD4 count ≥500/μL by study end point.

*p<0.05.

aOR, adjusted OR; HAART, highly active antiretroviral therapy.