Table 5.

Pooled estimates of diagnostic properties of the Patient Health Questionnaire-9 at cut-off point 10 and using algorithm scoring method in the non-independent vs independent studies groups

Settings	No. of studies	No. of patients	Sensitivity (95% CI)	Specificity (95% CI)	Pooled positive likelihood ratio (95% CI)	Pooled negative likelihood ratio (95% CI)	Diagnostic OR (95% CI)	Heterogeneity: I²
Manea et al, 2014 SR–RA group	7	4065	0.77 (0.70 to 0.84)	0.94 (0.90 to 0.97)	14.97 (8.39 to 26.71)	0.23 (0.17 to 0.31)	64.40 (34.15 to 121.43)	78.9%
Manea et al, 2014 SR Independent studies	21	9900	0.48 (0.41 to 0.91)	0.94 (0.91 to 0.95)	8.26 (6.15 to 11.09)	0.54 (0.48 to 0.62)	15.05 (11.03 to 20.52)	68.1%
Moriarty et al, 2015 SR–RA group	5	6188	0.87 (0.77 to 0.93)	0.87 (0.76 to 0.94)	7.24 (3.74 to 14.03)	0.14 (0.08 to 0.25)	49.31 (25.74 to 94.48)	55.1%
Moriarty et al, 2015 SR Independent studies	26	13 164	0.76 (0.67 to 0.83)	0.88 (0.85 to 0.91)	6.72 (5.06 to 8.92)	0.26 (0.19 to 0.37)	24.96 (14.81 to 42.08)	81.5%

SR, Systematic review; RA,researcher allegiance.