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. Author manuscript; available in PMC: 2017 Oct 13.
Published in final edited form as: Nat Cell Biol. 2017 Aug 21;19(9):1071–1080. doi: 10.1038/ncb3594

Figure 5. Condensin action is not required for mitotic cis-looping along chromosome arms.

Figure 5

a) Hi-C data collected from M phase cells following disruption of conDensin with smc2td GAL1-smc2K38I allele (MD). Chromosomes XIII to XVI are shown as representative of the whole genome. Contact maps were assembled from two independent experiments.

b) Log2 ratio of –condensin M dataset over wt M dataset (MD/M)

c) Contact probability (P(s)) for M and MD cells. The P(s) from each of the two independent experiments for each condition are shown.

d) Goodness-of-fit for simulated versus experimental intra-arm P(s), as in Figure 2, for conDensin depleted cells.