Table 1. Distribution of maternal characteristics by study site.
| Alexishafen, Papua New Guinea (n = 204) |
TMBA, Thailand (n = 118) |
|
|---|---|---|
| Maternal characteristics | ||
| Age (years) | 24 (21,28), [16–49] | 25 (21–32), [15–42] |
| Gravidity | 2 (1–4), [1–10] | 3 (2–5), [1–13] |
| Gestational age at delivery (weeks)a | 38 (37–40), [28–42] | 40 (40,41), [31–42] |
| Plasmodium spp. infection | ||
| P. falciparum infectionb | 81 (40) | 32 (27) |
| P. vivax infectionb | 12 (6) | 32 (27) |
| P. falciparum placental histology | ||
| No parasites detected | 92 (45) | Not determined |
| Parasites detected | 112 (55) | Not determined |
| Antibody measures | ||
| Maternal seropositive | ||
| PfEBA175RII IgG1 | 178 (87) | 43 (36) |
| PfEBA175RII IgG3 | 199 (98) | 114 (97) |
| PfAMA1 IgG1 | 197 (97) | 106 (90) |
| PfAMA1 IgG3 | 189 (93) | 91 (77) |
| PfMSP2 IgG1 | 199 (98) | 95 (81) |
| PfMSP2 IgG3 | 204 (100) | 106 (90) |
| PfDBL5 IgG1 | 119 (58) | 34 (29) |
| PfDBL5 IgG3 | 123 (60) | 74 (62) |
| Measles IgG1 | 195 (96) | 113 (96) |
| Measles IgG3 | 204 (100) | 117 (99) |
| Elevated serum IgGc | 50 (25) | 16 (14) |
NB—Data presented as median (inter-quartile range), [minimum-maximum] or n (%). Abbreviations: TMBA = Thailand-Myanmar Border Area.
a Estimated by Ballard scores in PNG, Dubowitz method in TMBA.
b Infection detected by light microscopy (peripheral) at any point during pregnancy. 7 and 11 women experienced a P. falciparum infection and a P. vivax infection during pregnancy in Papua New Guinea and Thailand respectively.
c Defined as a level of total IgG greater than the mean + three standard deviations of 15 Melbourne blood donors.