Table 2. Association of study site with maternofetal antibody transfer efficiency; estimated adjusted mean difference (95% confidence intervals) and p-values are presented.
PfEBA175RII−IgG1 | PfEBA175RII−IgG3 | PfAMA-1 –IgG1 | PfAMA-1 –IgG3 | PfMSP2 –IgG1 | PfMSP2 –IgG3 | PfDBL5 –IgG1 | PfDBL5 –IgG3 | Measles–IgG1 | Measles–IgG3 | |
---|---|---|---|---|---|---|---|---|---|---|
Adjusted1 | ||||||||||
TMBA | Reference | Reference | Reference | Reference | Reference | Reference | Reference | Reference | Reference | Reference |
PNG | -0.24 (-0.57,0.09); 0.16 |
-0.07 (-0.26,0.14); 0.53 |
-0.06 (-0.40,0.29); 0.75 |
-0.16 (-0.47,0.14); 0.29 |
-0.13 (-0.34,0.08); 0.22 |
0.09 (-0.12,0.29); 0.40 |
-0.28 (-0.64,0.07); 0.12 |
-0.88 (-1.11,-0.65); <0.001 |
-0.41 (-0.61,-0.21); <0.001 |
-0.26 (-0.39,-0.14); <0.001 |
Adjusted2 | ||||||||||
TMBA | Reference | Reference | Reference | Reference | Reference | Reference | Reference | Reference | Reference | Reference |
PNG | -0.11 (-0.45,0.23); 0.52 |
0.07 (-0.15,0.28); 0.53 |
0.10 (-0.25,0.45); 0.56 |
-0.03 (-0.35,0.29); 0.85 |
-0.04 (-0.26,0.19); 0.75 |
0.17 (-0.05,0.39); 0.14 |
-0.14 (-0.52,0.25); 0.48 |
-0.79 (-1.05,-0.53); <0.001 |
-0.34 (-0.56,-0.12); 0.002 |
-0.24 (-0.37,-0.11); 0.001 |
NB–Coefficients represent the differences in cord antibody levels by study site after adjustment for maternal antibody levels. Abbreviations: TMBA = Thailand-Myanmar Border Area; PNG = Papua New Guinea. 1 –Adjusted for log2 maternal levels. 2—Adjusted for log2 maternal levels, gravidity (primigravid/multigravid) and gestational age at delivery (weeks).