Table 2.

Observed mortality rates (per 100 person-years) and standardized mortality ratios (SMRs)^a by gender, duration since ART initiation and CD4 count at ART initiation^b.

	Males				Females
	Duration since ART initiation (months)				Duration since ART initiation (months)
	0–12	12–24	24–48	>48	0–12	12–24	24–48	>48
CD4 count <50 cells/µL
Observed mortality (crude)	19.54	5.55	4.07	2.69	16.93	4.26	2.55	1.66
Observed deaths	865	215	265	242	961	217	227	233
HIV-negative mortality (age standardized)	0.78	0.82	0.89	1.05	0.36	0.38	0.41	0.48
SMR	24.98	6.76	4.57	2.57	46.71	11.36	6.27	3.46
SMR 95% CI	23.31–26.64	5.86–7.67	4.02–5.12	2.25–2.9	43.76–49.67	9.84–12.87	5.46–7.09	3.02–3.91
CD4 count 50–199 cells/µL
Observed mortality (crude)	8.65	3.67	3.17	2.84	5.33	2.08	1.65	1.44
Observed deaths	871	336	494	545	1088	399	566	697
HIV-negative mortality (age standardized)	0.86	0.90	0.97	1.12	0.38	0.40	0.43	0.50
SMR	10.01	4.06	3.27	2.53	13.91	5.21	3.83	2.90
SMR 95% CI	9.35–10.68	3.62–4.49	2.98–3.56	2.32–2.74	13.09–14.74	4.7–5.72	3.52–4.15	2.69–3.12
CD4 count ≥200 cells/µL
Observed mortality (crude)	4.01	2.65	2.04	2.11	2.46	1.27	1.15	1.13
Observed deaths	191	104	115	81	357	154	202	143
HIV-negative mortality (age standardized)	0.85	0.88	0.95	1.10	0.37	0.38	0.42	0.47
SMR	4.73	3.01	2.15	1.92	6.74	3.31	2.76	2.39
SMR 95% CI	4.06–5.4	2.43–3.58	1.76–2.54	1.5–2.34	6.04–7.44	2.79–3.83	2.38–3.14	2.0–2.78

^aSMR: The number of observed deaths divided by the number of deaths expected if all patients were HIV negative.

^bExcludes 1228 patients who had no CD4 count at ART initiation.