Table 3.
Crude and adjusteda associations with mortality.
| Mortality |
||
|---|---|---|
| Univariate HR (95% CI) |
Multivariable aHR (95% CI) |
|
| Gender, male | 1.80 (1.74–1.87) | 1.41 (1.36–1.47) |
| Age (years) | ||
| 16–29 | 1 | 1 |
| 30–34 | 1.14 (1.07–1.21) | 1.04 (0.98–1.11) |
| 35–39 | 1.28 (1.20–1.35) | 1.12 (1.05–1.19) |
| 40–44 | 1.46 (1.37–1.56) | 1.28 (1.20–1.37) |
| 45–49 | 1.60 (1.49–1.72) | 1.40 (1.30–1.51) |
| 50–54 | 1.93 (1.79–2.11) | 1.71 (1.57–1.86) |
| 55–59 | 2.38 (2.18–2.66) | 2.10 (1.90–2.33) |
| 60–64 | 3.02 (2.68–3.53) | 2.63 (2.28–3.04) |
| 65+ | 3.87 (3.35–4.55) | 3.14 (2.68–3.67) |
| CD4 count (cells/µL) | ||
| <50 | 1 | 1 |
| 50–99 | 0.69 (0.65–0.73) | 0.74 (0.70–0.79) |
| 100–199 | 0.45 (0.44–0.49) | 0.56 (0.54–0.60) |
| ≥200 | 0.26 (0.25–0.29) | 0.40 (0.38–0.44) |
| WHO stage | ||
| I and II | 1 | 1 |
| III | 2.24 (2.12–2.37) | 1.55 (1.46–1.66) |
| IV | 3.26 (3.04–3.48) | 2.09 (1.93–2.26) |
| TB diagnosis | 1.62 (1.55–1.70) | 0.93 (0.88–0.99) |
| Weight, 10 kg | 0.71 (0.69–0.72) | 0.77 (0.76–0.79) |
| Year ART initiated | ||
| 2004–2006 | 1 | 1 |
| 2007–2009 | 1.00 (0.95–1.05) | 1.03 (0.98–1.14) |
| 2010–2012 | 0.73 (0.69–0.77) | 0.98 (0.92–1.03) |
| 2013–2015 | 0.47 (0.44–0.51) | 0.85 (0.78–0.92) |
| Site of ART initiation | ||
| Cohort 1 | 1 | 1 |
| Cohort 2 | 2.07 (1.88–2.28) | 1.91 (1.73–2.11) |
| Cohort 3 | 1.38 (1.25–1.53) | 1.36 (1.22–1.51) |
| Cohort 4 | 1.72 (1.56–1.90) | 1.46 (1.31–1.62) |
| Cohort 5 | 2.35 (2.09–2.64) | 1.83 (1.62–2.07) |
aAfter multiple imputation.