Table 1.
Demographic and clinical characteristics of study population by age groups
| Characteristics | Total | 60–69 years | 70–79 years | ≥80 years | P-value |
|---|---|---|---|---|---|
| Number | 21,723 | 11,835 (54.5%) | 7,373 (33.9%) | 2,515 (11.6%) | – |
| Age (years) | 70.70±7.35 | 64.99±2.98 | 75.34±2.90 | 83.95±2.86 | <0.001 |
| Female | 11,146 (51.3%) | 5,803 (49.0%) | 3,841 (52.1%) | 1,502 (59.7%) | <0.001 |
| Duration of T2DM (years) | 8.95±6.25 | 8.05±5.52 | 9.84±6.73 | 10.60±7.25 | <0.001 |
| Fasting glucose (mmol/L) | 8.11±2.80 | 8.17±2.77 | 8.11±2.81 | 7.85±2.89 | <0.001 |
| Waist circumference (cm) | 84.82±7.79 | 85.07±7.74 | 84.60±7.70 | 84.36±8.22 | <0.001 |
| Abdominal obesity | 11,353 (52.3%) | 6,175 (54.4%) | 3,784 (33.3%) | 1,394 (12.3%) | 0.002 |
| BMI (kg/m2) | 24.20±2.98 | 24.45±2.97 | 23.99±2.95 | 23.66±3.02 | <0.001 |
| <18.5 | 409 (1.9%) | 139 (1.2%) | 170 (2.3%) | 100 (4.0%) | <0.001 |
| 18.5–23.9 | 10,435 (48.0%) | 5,389 (45.5%) | 3,725 (50.5%) | 1,321 (52.5%) | – |
| 24–27.9 | 8,664 (39.9%) | 4,958 (41.9%) | 2,813 (38.2%) | 893 (35.5%) | – |
| ≥28 | 2,215 (10.2%) | 1,349 (11.4%) | 665 (9.0%) | 201 (8.0%) | – |
| Serum creatinine (mmol/L) | 77.98±25.55 | 75.08±22.99 | 80.07±26.65 | 85.48±31.04 | <0.001 |
| HbA1c (%) | 7.29±1.72 | 7.30±1.69 | 7.30±1.74 | 7.22±1.76 | 0.077 |
| HbA1c (%, ≤7.0%) | 11,663 (53.7%) | 6,312 (53.3%) | 3,931 (53.3%) | 1,420 (56.5%) | 0.012 |
| Hypertension (yes) | 13,112 (60.4%) | 6,361 (53.7%) | 4,953 (67.2%) | 1,798 (71.5%) | <0.001 |
| Albuminuria (ACR ≥30 mg/g) | 7,637 (35.2%) | 3,742 (31.6%) | 2,874 (39.0%) | 1,021 (40.6%) | <0.001 |
| eGFRCG (mL/min/1.73 m2) | 70.20±18.18 | 78.67±16.05 | 63.18±14.45 | 50.92±13.26 | <0.001 |
| eGFRBIS1 (mL/min/1.73 m2) | 70.11±15.48 | 77.35±13.53 | 63.87±12.49 | 54.35±11.93 | <0.001 |
| eGFRmMDRD (mL/min/1.73 m2) | 91.61±23.04 | 96.50±21.88 | 87.78±22.54 | 79.82±23.38 | <0.001 |
| eGFRMDRD (mL/min/1.73 m2) | 83.86±20.73 | 88.46±19.79 | 80.29±20.09 | 72.69±20.63 | <0.001 |
| eGFRCKD-EPI (mL/min/1.73 m2) | 78.23±16.41 | 83.79±14.40 | 73.81±15.49 | 64.97±16.38 | <0.001 |
| eGFRCKD-EPI-Asia (mL/min/1.73 m2) | 82.36±17.35 | 88.23±15.25 | 77.70±16.37 | 68.35±17.29 | <0.001 |
| eGFRRuijin (mL/min/1.73 m2) | 76.91±15.29 | 80.97±14.25 | 73.67±14.68 | 67.32±15.28 | <0.001 |
Notes: Data are means ± SD or n (%). All percentages are column percentage.
Abbreviations: ACR, albumin to creatinine ratio; BIS1, Berlin Initiative Study 1 equation; BMI, body mass index; CG, Cockcroft–Gault equation; CKD-EPI, chronic kidney disease epidemiology collaboration; CKD-EPI-Asia, CKD-EPI equation in Asians; Chinese-Ruijin, Ruijin equation; eGFR, estimated glomerular filtration rate; HbA1c, hemoglobin A1c; MDRD, modification of diet in renal disease equation; mMDRD, MDRD modified for Chinese equation; T2DM, type 2 diabetes mellitus.