Table 1.
Demographic characteristics of 25 subjects with CKD and 10 healthy controls
| Parameters | Healthy controls | Mild CKD | Moderate to severe CKD | Note |
|---|---|---|---|---|
| Gender (M/F) | 5/5 | 3/8 | 10/4 | 13/12 |
| Age | 39±16 | 55±16 | P= .02 | |
| eGFR (mL/min/1.73 m2) | >60 | 59.9±0.32 | 33.87±14.14 | P< .001 |
| Body mass index (BMI) | 27.8±4.9 | 28.7±5.4 | 28.8±5.8 | P= .95 |
| CKD stage | ≤ II | III and IV | ||
| Etiology | Total | |||
| Diabetic nephropathy | 1 | 3 | 4 | |
| Glomerulonephritis | 1 | 1 | 2 | |
| Lupus nephritis | 1 | 2 | 3 | |
| Ig A nephritis | 1 | 1 | 2 | |
| Hypertensive nephrosclerosis | 0 | 5 | 5 | |
| Membranous | 2 | 0 | 2 | |
| Toxic and non-specific | 4 | 3 | 7 | |
| Race | Total | |||
| African American | 2 | 2 | 3 | 5 |
| Asian | 2 | 1 | 1 | 2 |
| Latino | 2 | 1 | 2 | 3 |
| White | 3 | 4 | 4 | 8 |
| Mixed and others | 1 | 2 | 5 | 7 |
Note: Based on all scores of four kidney biopsy pathology parameters (glomerulosclerosis, arteriosclerosis, IF/TA, and interstitial inflammation), a pathologic mild CKD (Mild CKD) is for those with no grade 3 and < 2 of grade 2; and a pathologic moderate to severe CKD is for those with at least 2 of grade 2 or 1 of grade 3.