Figure 4. The concordance index for each of the models tested over time.

The full models (models with all 735 variables) did not converge for the LASSO-Cox, AIC-Cox and the Cox PHM models, and hence are not shown here. The prediction ability of conventional risk scores for heart failure (MESA HF risk score), cardiovascular disease (AHA/ASCVD risk score) and coronary heart disease (Framingham CHD risk score) are also shown (yellow curve). In general, the C-index for all variables decreased over time.