Table 2. Putative transcription factor binding sites within the proximal Gng11 promoter*.

Factor Name	Position (strand)	Core Match	Matrix Match	Sequence (+ strand)
Pax-4	-1763 (+)	0.979	0.890	attagTCAGGcgtggtagcgg
FOXD3	-1086 (+)	1.000	0.982	caTTGTTttttt
Pax-4	-993 (+)	1.000	0.835	aatggTCATGggtgtcttggg
HNF-1	-952 (+)	1.000	0.862	aGTTAAtatttcacttg
Pax-6	-863 (+)	0.842	0.849	tacatTCATGtttgatttttc
Pax-4	-631 (+)	0.986	0.856	tggtgTCAAGtgtcacccaaa
Nkx2-5	-626 (+)	1.000	1.000	tcAAGTG

*The proximal 2000 bp upstream of the gene Gng11 was downloaded from the hg38 build of the human genome using the UCSC Genome Browser [51]. This sequence was used to query the Transfac 6.0 database using Match v.1.0 [52]. Only vertebrate matrices noted as “high quality” were used, and the cut-off selection for matrix groups was set to minimize false positives. * Position is given relative to the transcriptional start site. Matrix match is a score that describes the quality of a match between a positional weight matrix in TRANSFAC 6.0 and the input sequence. Core match denotes the quality of a match between the core sequence of a transcription factor binding site and the input sequence. For each, a score of 1 denotes an exact match. Capitalized letters in the sequence match the core sequence of the matrix, while the remaining positions of a matrix are lower case.