Table 3.
SNPs | Groups | Additive model | Dominant model | Recessive model | |||
---|---|---|---|---|---|---|---|
Pc | OR (95%CI) | Pc | OR (95%CI) | Pc | OR (95%CI) | ||
rs6590330 | PM | 0.127 | 1.20(1.00–1.43) | 0.029 | 1.37(1.08–1.74) | NS | 1.03(0.71–1.50) |
DM | 0.030 | 1.20(1.04–1.39) | 0.038 | 1.28(1.05–1.55) | 0.405 | 1.25(0.93–1.66) | |
IIM | 0.010 | 1.20(1.06–1.36) | 4.86 × 10 −3 | 1.31(1.11–1.55) | 0.704 | 1.17(0.90–1.51) | |
rs7117932 | PM | 0.577 | 1.13(0.94–1.36) | 0.160 | 1.26(1.00–1.59) | NS | 0.85(0.52–1.39) |
DM | 8.79 × 10 −3 | 1.25(1.08–1.45) | 8.37 × 10 −3 | 1.33(1.10–1.61) | 0.427 | 1.30(0.92–1.85) | |
IIM | 0.013 | 1.21(1.06–1.38) | 4.54 × 10 −3 | 1.31(1.11–1.54) | NS | 1.13(0.83–1.57) | |
rs4937362 | PM | 0.202 | 0.85(0.71–1.01) | 0.312 | 0.82(0.65–1.04) | 0.551 | 0.76(0.51–1.14) |
DM | 0.593 | 0.91(0.79–1.05) | 0.886 | 0.90(0.75–1.09) | 0.821 | 0.84(0.61–1.15) | |
IIM | 0.179 | 0.89(0.78–1.00) | 0.334 | 0.87(0.74–1.03) | 0.403 | 0.81(0.62–1.07) |
Bold values are statistically significant (P < 0.05) (corrected for multiple comparisons by the Bonferroni adjustment test).
PM: polymyositis; DM: dermatomyositis; IIM: idiopathic inflammatory myopathies; OR odds ratio; CI confidence interval; Pc: P value corrected by Bonferroni method; NS: not significant.