Transduced lentivirus are indicated in the upper panel; A= Transcription assays by quantitative RT PCR, RNA data from two biological replicates were analyzed in triplicates, normalized to ACTB expression and expressed as fold of expression to non-transduced control cells; B= Assays of mitochondrial activities, data from two biological replicates analyzed twice
C= Control cells; P=Patient’s cells; non-transduced cells = white bars for the control, black bars for the patient; cells transduced with LYRM7-lentivirus = bars with horizontal lines, with MTO1-lentivirus = bars with vertical lines, with both LYRM7- and MTO1-lentiviruses = bars with diagonal lines *=p<0.05, **=p<0.01, ***=p<0.001 as compared to non-transduced control cells unless otherwise specified with brackets.