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. Author manuscript; available in PMC: 2018 Mar 1.
Published in final edited form as: J Hepatol. 2016 May 2;65(2):377–385. doi: 10.1016/j.jhep.2016.04.017

Figure 4. LYRM7 expression restored UQCRFS1 expression.

Figure 4

A= Representative western blot analysis of purified mitochondria from control (C) and Patient (P) fibroblasts transduced with either LYRM7- or MTO1-lentivirus, alone or in association, as indicated below the western blot; specific bands are indicated with an arrow on the left side; B=quantification of the protein steady-state normalized to SDHA and to the non-transduced control mitochondria of the same gel; data from five independent experiments for LYRM7, MTO1, and UQCRFS1 and from two for UQCRC2; C= Control; P=Patient; mitochondria from non-transduced cells = white bars for control cells and black bars for patient’s cells; mitochondria from cells transduced with LYRM7-lentivirus = bars with horizontal lines, with MTO1-lentivirus = bars with vertical lines, with both LYRM7- and MTO1-lentiviruses = bars with diagonal lines; *=p<0.05, **=p<0.01, ***=p<0.001 as compared to non-transduced control cells.