FIG 5.

Sorafenib treatment prevents Gn from colocalizing with the Golgi complex in Huh7 cells. Huh7 cells were infected with MP12 at an MOI of 10 and either treated with DMSO immediately following infection (A) or treated with sorafenib immediately following infection (B). Cells were fixed, permeabilized, and stained for Gn, trans-Golgi network protein 46 (TGN46), and Hoechst at 12 h postinfection. Arrowheads indicate areas of TGN46 and Gn colocalization (A) or areas that lack TGN46 and Gn colocalization (B).