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Endoglin-specific siRNA inhibits downstream ID1 signaling molecules in HCV-infected or core-transfected cells. The P-SMAD1/5, ID1, or Bcl2 status was altered upon treatment of HCV-infected (A) or core-transfected (B) cells with endoglin siRNA. Actin was detected and used as an internal control for densitometric scanning and comparison of protein status (shown on the right). Statistical significance was analyzed using the two-tailed Student t test: *, P < 0.05; **P < 0.01.
