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Single-step growth curves of the NSP6-deficient viruses in IFN-α/β-deficient Vero E6 cells. Vero E6 cells were infected with rSA11 or rSA11-delNSP6 (A) or with rSA11-s11KU or rSA11-s11KU-delNSP6 (B) at an MOI of 5 and then incubated for various times. The virus titers in the cultures were determined by plaque assay. The data shown are the mean viral titers and SDs from three independent cell cultures.
