FIG 6.

Proliferation of lymphocytes in LNs and PBMCs as measured by flow cytometry. (A) Ki-67 immunostaining of lymphocytes isolated from LNs of healthy animals on day −18 preexposure (n = 2) and from LNs of surviving animals (n = 4) on days 9 and 22 p.i. (B to D) Ki-67 immunostaining of CD4⁺ T cells (B), CD8⁺ T cells (C), and CD20⁺ B cells (D) in PBMCs in treated and untreated survivors versus moribund NHPs. Abbreviations: LN, lymph node; NHP, nonhuman primate; PBMCs, peripheral blood mononuclear cells; p.i., postinfection.