TABLE 2.
Polymorphisms observed among CyHV-3 strains in ORFs encoding VTPs
| Gene | Requirement in FL strain | Mutationa |
|---|---|---|
| ORF32 | Essential | No mutation |
| ORF59 | Essential | No mutation |
| ORF81 | Essential | No mutation |
| ORF83 | Essential | Several aa inserted in M3, T, and J |
| ORF99 | Essential | Several aa changed in KHV-I, M3, T, and J |
| ORF106 | Essential | No mutation |
| ORF115 | Essential | One aa changed in T |
| ORF131 | Essential | One aa changed in KHV-I, FL, Cavoy, and T |
| ORF25 | Nonessential | Several aa inserted in M3, T, J, and GZ11 |
| ORF27 | Nonessential | Frameshifted in U, KHV-I, T, and GZ11; large regions deleted in FL; stop codon insertion in the beginning of the ORF in Cavoy; several aa changed in M3 and J |
| ORF64 | Nonessential | Frameshifted and several amino acids deleted or inserted in M3, T, and J |
| ORF65 | Nonessential | One aa deleted in KHV-I, FL, Cavoy, I, and E; one aa inserted and several aa deleted in M3, T, and J; one aa changed in GZ11 |
| ORF108 | Nonessential | One aa inserted, one aa changed and a stop codon inserted at the end of the ORF, several aa lost in M3, T, and J |
| ORF132 | Nonessential | One aa changed in KHV-I |
| ORF136 | Nonessential | Several aa inserted and a stop codon inserted in the middle of the ORF in M3, T, and J |
| ORF148 | Nonessential | Several aa inserted in KHV-I, Cavoy, and GZ11; Several aa deleted in M3, T, and J |
| ORF149 | Nonessential | One aa changed in KHV-I, Cavoy, and E, 13 aa inserted in M3 and J |
a
Boldfacing indicates mutations that create an in-frame stop codon or frameshift. aa, amino acid(s).