Figure 1.

Curcumin increased the cell viability, decreased the number of autophagosomes, and increased lysosomal Ca²⁺ levels in amyloid-β1-42 (Aβ1-42)-treated HT-22 cells. (A) Curcumin significantly increased cell viability, with the maximum cell viability was observed at a concentration of 10 μM. (B) The results of transmission electron microscopic examination showed that curcumin decreased the number of autophagosomes in Aβ1-42-treated HT-22 cells. (C) Curcumin significantly increased lysosomal Ca²⁺ levels and the highest level was observed at a concentration of 10 μM. ^#p < 0.05 compared to the Aβ1-42 control.