Table 4.

Results of the longitudinal epigenome-wide association studies (EWAS)

DNA methylation	Asthma definition	N [cases/controls]	Cell adjustment	FDR hits [Bonferroni]	Lambda
7.5 years	Current asthma at 16.5 years	611 [182/429]	No cells	4 [2]	1.11
			Basic cells	9 [2]	1.13
			Detailed cells	0 [0]	1.10
16.5 years	Current asthma at 7.5 years	784 [146/638]	No cells	28 [0]	1.24
			Basic cells	1 [1]	1.16
			Detailed cells	0 [0]	1.14

FDR-adjusted P value and Bonferroni hits use a cut-off of < 0.05