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. 2017 Apr 20;8(42):71489–71499. doi: 10.18632/oncotarget.17288

Figure 8. Schematic illustration of how CVV can target and kill the metastatic HCC by overcoming limited effects of anticancer drugs.

Figure 8

The CVV has enhanced cancer-favoring selectivity and cytotoxicity toward metastatic liver cancer stem cells with high EMT & cTk expression, because of its cancer-favoring characteristics and the different cytotoxic pathway used to kill cancer cells.