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. 2017 May 10;8(42):71563–71573. doi: 10.18632/oncotarget.17751

Figure 1. Lack of IL-35 expression correlated with the poor prognosis of colon cancer.

Figure 1

(A) IL-35 mRNA levels in cancer tissues and adjacent normal tissues were determined by real-time PCR (n = 186). *P < 0.05. (B) IL-35 protein levels in cancer tissues and adjacent normal tissues were determined by ELISA (n = 186). Result is depicted as box plots; middle line indicates median; bottom of box, 25th percentile; and top of box, 75th percentile. *P < 0.05. (C) Representative figure for IL-35 protein levels in cancer tissues and adjacent normal tissues were determined by western blot. N: adjacent normal tissues; C: cancer tissues. (D) Kaplan-Meier survival curve of patients with negative, weak or strong expression of IL-35.